Architecting a VMware NSX Solution : Design Considerations : 4.4 vSphere Cluster Design : 4.4.1 Design Considerations
   
4.4.1 Design Considerations
For increased availability, distribute cluster hosts across racks within the data center so that a rack failure has limited impact on your cluster operation.
For large deployments, consider deploying an NSX Edge cluster for all networking services appliances for North/South traffic. This enables the provider to be deterministic as to where network traffic exits the data center and limits the need to present service VLANs to all payload hosts.
If leaf-and-spine network topology is leveraged and management hosts are distributed across racks, verify that the management L2 networking is extended across the racks so that the management network is available in both racks.