Architecting a VMware NSX Solution : Design Considerations : 4.3 vCenter Server Design : 4.3.1 Design Considerations
   
4.3.1 Design Considerations
NSX Manager instances pair with the vCenter Server instances on a 1:1 basis, so the VMware NSX solution scales in a modular fashion with the vCenter Server and can be implemented on a Pod-based approach to scalability that includes network and security services.
Avoid pairing the management vCenter Server with an NSX Manager because this could lead to a circular dependency impacting the management components with the distributed firewall.