Architecting a VMware NSX Solution : Deployment Model Considerations : 3.1 Deployment Sizing Considerations
   
3.1 Deployment Sizing Considerations
The configuration of the VMware NSX for your cloud and hosting offering can be categorized into two main scenarios—deployment in small/medium data centers and deployment in large-scale data centers. The following considerations are valid when deploying VMware NSX in both scenarios:
VMware vCenter Server® and NSX Manager 6.1.x have a one-to-one mapping relationship. That is, there is one NSX Manager (NSX domain) per vSphere or vCenter Server instance. (This implies the scale limit of vCenter Server governs the scale of the overall VMware NSX deployment.)
As part of the installation process, NSX Controller instances must be deployed on the same vCenter Server that NSX Manager is connected to.
The main difference in small/medium data center compared with large-scale data center designs is usually the number of vCenter Server instances deployed and how they map to NSX Manager.
Note VMware NSX version 6.2 can support multiple vCenter Server instances. This is out of scope for this version of the document.